Reduction in urinary tract infections in patients treated with fecal microbiota transplantation for recurrent Clostridioides difficile infection

Raseen Tariq; Pritish K Tosh; Darrell S Pardi; Sahil Khanna

doi:10.1007/s10096-023-04635-4

Reduction in urinary tract infections in patients treated with fecal microbiota transplantation for recurrent Clostridioides difficile infection

Eur J Clin Microbiol Infect Dis. 2023 Aug;42(8):1037-1041. doi: 10.1007/s10096-023-04635-4. Epub 2023 Jun 23.

Authors

Raseen Tariq¹, Pritish K Tosh², Darrell S Pardi¹, Sahil Khanna³

Affiliations

¹ Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
² Division of Infectious Diseases, Mayo Clinic, Rochester, MN, USA.
³ Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA. [email protected].

PMID: 37351724
DOI: 10.1007/s10096-023-04635-4

Abstract

We performed an updated study to investigate the rates of urinary tract infections (UTIs) in patients with recurrent Clostridioides difficile infection (CDI) who received fecal microbiota transplantation (FMT) for CDI. We found a significant reduction in number of UTIs after FMT compared to patients who received antibiotics for CDI treatment. After FMT, we also observed a trend towards reduction of antibiotic resistance in organisms causing UTI.

MeSH terms

Clostridioides difficile*
Clostridium Infections* / microbiology
Fecal Microbiota Transplantation / adverse effects
Humans
Recurrence
Treatment Outcome
Urinary Tract Infections* / etiology
Urinary Tract Infections* / therapy