Case series of aspergillus spondylodiscitis from a tertiary care centre in India

Indian J Med Microbiol. 2023 Jul-Aug:44:100363. doi: 10.1016/j.ijmmb.2023.02.006. Epub 2023 May 11.

Abstract

Aspergillus spondylodiscitis is a rare entity reported in the literature. In tuberculosis endemic regions like India, more often it could be misdiagnosed as tuberculous spondylodiscitis. Herein we report a case series of three patients with Aspergillus spondylodiscitis presenting with chronic low backpain and clinically diagnosed as tuberculosis spine. Culture and histopathological examination of the debrided tissue provided a definite diagnosis. Interestingly, one of the cases had coexisting tuberculosis spine. All three patients underwent surgical intervention-debridement, decompression and fusion of spine and combined medical management with voriconazole with successful outcome.

Keywords: Aspergillus; Spondylodsicitis; Voriconazole.

Publication types

  • Case Reports

MeSH terms

  • Aspergillus
  • Discitis* / diagnosis
  • Discitis* / surgery
  • Humans
  • Lumbar Vertebrae
  • Tertiary Care Centers
  • Voriconazole / therapeutic use

Substances

  • Voriconazole