Combined exposure to the alarmins TSLP, IL-33 and IL-25 enhances mast cell-dependent contractions of human bronchi

Clin Exp Allergy. 2023 Oct;53(10):1062-1066. doi: 10.1111/cea.14367. Epub 2023 Jun 28.

Authors

Maria Belikova^{1

2}, Jesper Säfholm^{1

2}, Mamdoh Al-Ameri^{3

4}, Ann-Charlotte Orre⁴, Sven-Erik Dahlén^{1

2

5}, Mikael Adner^{1

2}

Affiliations

¹ Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden.
² Centre for Allergy Research, Karolinska Institute, Stockholm, Sweden.
³ Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.
⁴ Heart and Vascular Theme, Karolinska University Hospital, Stockholm, Sweden.
⁵ Department of Respiratory Medicine, Karolinska University Hospital, Stockholm, Sweden.

PMID: 37377053
DOI: 10.1111/cea.14367

No abstract available

Keywords: IL-33; TSLP; airway hyperresponsiveness; anti-IgE; asthma; histamine; prostaglandin D2.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Alarmins*
Asthma*
Bronchi
Cytokines
Humans
Interleukin-33
Mast Cells

Substances

Alarmins
Interleukin-33
Cytokines