Znic (Zn) alloys with good cytocompatibility and suitable degradation rate have been a kind of biodegradable metal with great potential for clinical applications. This paper summarizes the biological role of degradable Zn alloy as bone implant materials, discusses the mechanical properties of different Zn alloys and their advantages and disadvantages as bone implant materials, and analyzes the influence of different processing strategies (such as alloying and additive manufacturing) on the mechanical properties of Zn alloys. This paper provides systematic design approaches for biodegradable Zn alloys as bone implant materials in terms of the material selection, product processing, structural topology optimization, and assesses their application prospects with a view to better serve the clinic.
锌(Zn)合金具有良好的细胞相容性和适宜的降解速率,是一种极具临床应用前景的生物可降解金属。本文总结了可降解Zn合金作为骨植入材料的生物学作用,归纳了不同Zn合金材料的力学性能及其作为骨植入材料的优缺点,分析了不同加工策略(如合金化、增材制造等)对Zn合金力学性能的影响。全文从材料选择、产品加工处理及结构拓扑优化等方面为生物可降解Zn合金骨植入材料提供了系统化的设计思路,并对其应用前景进行了展望,以期更好地服务于临床。.
Keywords: Additive manufacturing; Alloying; Mechanical property; Orthopedic implants; Zinc alloy.