currently Celiac Disease corresponds to an entity mainly managed by expert gastroenterologists on the topic but which must be faced on many occasions by primary care physicians or general gastroenterologists. It is important for a good diagnosis to look closely at all the factors that lead to a correct diagnosis (manifestations, antibodies, biopsy). In the spectrum of manifestations we find the classic ones, where the patient suffers from gastrointestinal symptoms typical of a classic Celiac Disease. At the same time, it is important to know that some of these patients do not have these classic symptoms and sometimes their only expression is neurological.