Early pregnancy complications including recurrent pregnancy loss and obesity

Best Pract Res Clin Obstet Gynaecol. 2023 Aug:90:102372. doi: 10.1016/j.bpobgyn.2023.102372. Epub 2023 Jun 23.

Abstract

This review on early pregnancy complications and obesity will focus on the known pregnancy complications such as miscarriage (whether spontaneous or after fertility treatment), polycystic ovaries and risk of miscarriage, recurrent pregnancy loss, ectopic pregnancy, hyperemesis gravidarum and birth defects. Evidence will be assessed and mechanistic pathways for the outcomes will be described. We know that obesity is now a pandemic and has an impact on early pregnancy complications. The evidence has been summarised to provide the reader with a comprehensive overview and advice for pregnant women with obesity in early pregnancy.

Keywords: Early pregnancy; Ectopic pregnancy; Miscarriage; Obesity; PCOS; Repeated pregnancy loss.

Publication types

  • Review

MeSH terms

  • Abortion, Habitual* / etiology
  • Abortion, Habitual* / prevention & control
  • Abortion, Spontaneous*
  • Female
  • Humans
  • Infertility, Female* / etiology
  • Obesity / complications
  • Obesity / epidemiology
  • Obesity / therapy
  • Ovulation Induction / adverse effects
  • Polycystic Ovary Syndrome* / complications
  • Polycystic Ovary Syndrome* / therapy
  • Pregnancy
  • Pregnancy Complications* / etiology
  • Pregnancy Complications* / therapy
  • Pregnancy Rate