Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging

Nat Methods. 2023 Aug;20(8):1174-1178. doi: 10.1038/s41592-023-01846-7. Epub 2023 Jul 19.

Abstract

Multiplexed antibody-based imaging enables the detailed characterization of molecular and cellular organization in tissues. Advances in the field now allow high-parameter data collection (>60 targets); however, considerable expertise and capital are needed to construct the antibody panels employed by these methods. Organ mapping antibody panels are community-validated resources that save time and money, increase reproducibility, accelerate discovery and support the construction of a Human Reference Atlas.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, N.I.H., Extramural
  • Research Support, N.I.H., Intramural

MeSH terms

  • Antibodies*
  • Community Resources*
  • Diagnostic Imaging
  • Humans
  • Reproducibility of Results

Substances

  • Antibodies