TGF-β: the apex predator of immune checkpoints

Future Oncol. 2023 Sep;19(30):2013-2015. doi: 10.2217/fon-2023-0491. Epub 2023 Jul 28.

Authors

Bryan Oronsky¹, Pedro Cabrales², Babak Alizadeh¹, Scott Caroen¹, Meaghan Stirn¹, Jeannie Williams¹, Tony R Reid¹

Affiliations

¹ Department of Research and Development, EpicentRx, Inc. Torrey Pines, CA 92037, USA.
² Department of Bioengineering, University of California at San Diego (UCSD) La Jolla, CA 92093, USA.

PMID: 37503560
DOI: 10.2217/fon-2023-0491

No abstract available

Keywords: AdAPT-001; ICD; RRx-001; TGF-β; immunogenic cell death.

MeSH terms

Humans
Immunotherapy
Transforming Growth Factor beta*
Tumor Microenvironment*

Substances

Transforming Growth Factor beta