Introduction: Antegrade dissection and re-entry (ADR) is an integral part of the hybrid algorithm, which has allowed for improved outcomes in chronic total occlusion (CTO) coronary intervention (PCI).
Methods: A new ADR method, Subintimal Antegrade FEnestration and Re-entry (SAFER), is described. The results of a first-in-man series are presented.
Results: SAFER was performed on seven consecutive patients with angiographic and clinical success in all patients.
Conclusions: This first-in-man study has shown that the SAFER technique is feasible and effective with the possibility of improving the antegrade PCI CTO success rate.
Keywords: antegrade dissection re-entry; chronic total occlusion; percutaneous coronary intervention.
© 2023 The Authors. Catheterization and Cardiovascular Interventions published by Wiley Periodicals LLC.