Management of an Esophago-pleural Fistula after Emergent Endoscopic Variceal Injectional Sclerotherapy: A Case Report And Literature Review

Intern Med. 2024 Apr 1;63(7):937-941. doi: 10.2169/internalmedicine.1961-23. Epub 2023 Aug 16.

Abstract

A 48-year-old man developed sudden-onset haematemesis and melena after decompensated posthepatitic cirrhosis. Endoscopic variceal injectional sclerotherapy was emergently performed. However, the patient developed esophago-pleural fistula, empyema, and liver failure. He thus received symptomatic treatments and nasojejunal feedings, which failed to restore the nutrition as the gastroesophageal reflux exacerbated the hydrothorax. Percutaneous endoscopic gastro-jejunal (PEG-J) was therefore carefully performed for enteral nutrition support. The patient had recovered from the fistula at a six-month follow-up, which allowed the resumption of an oral diet. Our literature review revealed that PEG-J is a feasible approach to treating esophago-pleural fistula, a rare but lethal complication of endoscopic sclerotherapy.

Keywords: endoscopic variceal injectional sclerotherapy; enteral nutrition; esophago-pleural fistula; healing; pleural effusion.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Empyema* / complications
  • Endoscopy / adverse effects
  • Esophageal and Gastric Varices* / complications
  • Esophageal and Gastric Varices* / therapy
  • Fistula* / complications
  • Fistula* / therapy
  • Gastrointestinal Hemorrhage / complications
  • Humans
  • Male
  • Middle Aged
  • Pleural Diseases* / therapy
  • Sclerotherapy / adverse effects