Chemogenetic activation of G
12
signaling enhances adipose tissue browning
Signal Transduct Target Ther
.
2023 Aug 21;8(1):307.
doi: 10.1038/s41392-023-01524-2.
Authors
Yuki Ono
1
,
Ryo Ito
#
2
,
Kaito Arai
#
1
,
Gurdeep Singh
3
4
,
Tsuyoshi Saitoh
5
6
,
Robert B Russell
3
4
,
Francesco Raimondi
7
,
Junken Aoki
8
,
Juro Sakai
2
9
,
Asuka Inoue
10
Affiliations
1
Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, 980-8578, Japan.
2
Division of Molecular Physiology and Metabolism, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, 980-8574, Japan.
3
Bioquant, Heidelberg University, Im Neuenheimer Feld 267, 69120, Heidelberg, Germany.
4
Biochemie Zentrum Heidelberg (BZH), Heidelberg University, Im Neuenheimer Feld 328, 69120, Heidelberg, Germany.
5
International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.
6
Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.
7
Laboratorio di Biologia Bio@SNS, Scuola Normale Superiore, Piazza dei Cavalieri 7, Pisa, 56126, Italy.
8
Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, 113-0033, Japan.
9
Division of Metabolic Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, Meguro-ku, Tokyo, 153-8904, Japan.
10
Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, 980-8578, Japan.
[email protected]
.
#
Contributed equally.
PMID:
37599327
PMCID:
PMC10440338
DOI:
10.1038/s41392-023-01524-2
No abstract available
Publication types
Letter
Research Support, Non-U.S. Gov't
MeSH terms
Adipose Tissue, Brown* / physiology
GTP-Binding Proteins* / genetics
Signal Transduction* / genetics
Substances
GTP-Binding Proteins