Deposition of complement components C5b-9 and MASP2 in tissues is not a feature of GVHD and may assist in discriminating GVHD from thrombotic microangiopathy following allogenic transplantation

Bone Marrow Transplant. 2023 Nov;58(11):1270-1274. doi: 10.1038/s41409-023-02089-y. Epub 2023 Aug 21.

Affiliations

¹ Division of Hematology and Oncology, Department of Medicine, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY, USA. [email protected].
² Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
³ Division of Hematology and Oncology, Department of Medicine, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY, USA.

PMID: 37604872
DOI: 10.1038/s41409-023-02089-y

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Complement Membrane Attack Complex
Graft vs Host Disease* / diagnosis
Graft vs Host Disease* / etiology
Humans
Mannose-Binding Protein-Associated Serine Proteases
Thrombotic Microangiopathies* / diagnosis
Thrombotic Microangiopathies* / etiology

Substances

Complement Membrane Attack Complex
MASP2 protein, human
Mannose-Binding Protein-Associated Serine Proteases