Gender Differences in Premenstrual Syndrome and Premenstrual Dysphoric Disorder Diagnosis and Treatment among Japanese Obstetricians and Gynecologists: A Cross-Sectional Study

Tohoku J Exp Med. 2023 Oct 7;261(2):95-101. doi: 10.1620/tjem.2023.J059. Epub 2023 Aug 23.

Abstract

Premenstrual symptoms are characterized by unpleasant psychophysical symptoms that appear during the luteal phase before menstruation and interfere with a woman's quality of life. Premenstrual syndrome (PMS) is a pathological condition with premenstrual symptoms, of which premenstrual dysphoric disorder (PMDD) is a particularly severe psychological symptom. This study aimed to examine the gender differences in the diagnosis and treatment of PMS and PMDD among obstetricians and gynecologists (OB/GYNs) in Japan. Data were obtained from the survey conducted by the Japanese Society of Obstetrics and Gynecology. We used data from 1,257 of the 1,265 OB/GYNs who are engaged in PMS/PMDD practice and reported their gender. Multivariate regression analysis adjusted for propensity scores was performed. Female OB/GYNs were more frequently engaged in treating patients with PMS/PMDD than males [odds ratio (OR) 1.74; 95% confidence interval (CI) 1.36-2.21]. With regard to the diagnostic methods, more female OB/GYNs selected the two-cycle symptom diary than males (OR 2.88; 95% CI 1.80-4.60). Regarding treatment, fewer female OB/GYNs selected selective serotonin reuptake inhibitors as their first-line drug (OR 0.39; 95% CI 0.17-0.89). Gender differences were found in the selection of PMS/PMDD diagnosis and treatment methods among Japanese OB/GYNs.

Keywords: doctor-patient relationships; gender; oral contraceptive pills; prospective symptom diary; selective serotonin reuptake inhibitor.

MeSH terms

  • Cross-Sectional Studies
  • East Asian People
  • Female
  • Gynecologists
  • Health Knowledge, Attitudes, Practice
  • Humans
  • Japan / epidemiology
  • Male
  • Obstetricians
  • Premenstrual Dysphoric Disorder* / diagnosis
  • Premenstrual Dysphoric Disorder* / epidemiology
  • Premenstrual Dysphoric Disorder* / therapy
  • Premenstrual Syndrome* / diagnosis
  • Premenstrual Syndrome* / epidemiology
  • Premenstrual Syndrome* / therapy
  • Quality of Life
  • Sex Factors