Depression and anxiety in patients with head and neck cancer undergoing free flap reconstruction

Am J Otolaryngol. 2024 Jan-Feb;45(1):104044. doi: 10.1016/j.amjoto.2023.104044. Epub 2023 Sep 12.

Abstract

Purpose: To determine the prevalence and severity of depression and anxiety in patients with head and neck cancer (HNC) undergoing treatment with free-flap (FF) reconstruction.

Methods: Participants with HNC undergoing FF reconstruction were given the validated 9-item Patient Health Questionnaire (PHQ-9) and a 7-item Generalized Anxiety Disorder (GAD-7) questionnaire prior to surgery. Patient factors and responses were analyzed.

Results: Seventy-one patients were included. Mean (SD) pre-operative PHQ-9 was 7.6 (7.04) with 34 % (n = 24) having moderate to severe depression. Mean (SD) pre-operative GAD-7 was 6.5 (6.86) with 30 % (n = 21) having moderate to severe anxiety.

Conclusion: Prevalence of depression and anxiety is high in this cohort and undiagnosed in 22 % and 18 % of patients, respectively. Due to the findings, it is prudent to screen HNC patients at initial diagnosis and offer mental health services.

Keywords: Anxiety; Depression; Free flap reconstruction; Head and neck cancer.

MeSH terms

  • Anxiety / diagnosis
  • Anxiety / epidemiology
  • Anxiety / etiology
  • Anxiety Disorders / diagnosis
  • Anxiety Disorders / epidemiology
  • Anxiety Disorders / etiology
  • Depression / epidemiology
  • Depression / etiology
  • Free Tissue Flaps*
  • Head and Neck Neoplasms* / surgery
  • Humans