We report the clonal spread and evolution of high-risk Pseudomonas aeruginosa sequence type 463 co-producing KPC-2 and AFM-1 carbapenemases isolated from hospital patients in China during 2020-2022. Those strains pose a substantial public health threat and surveillance and stricter infection-control measures are essential to prevent further infections.
Keywords: AFM-1; China; KPC-2; Pseudomonas aeruginosa; ST463; antimicrobial resistance; bacteria; blaAFM-1; blaKPC-2; carbapenemase; clonal spread; respiratory infections; sequence type.