British Society of Gastroenterology guidelines for the diagnosis and management of cholangiocarcinoma

Simon M Rushbrook; Timothy James Kendall; Yoh Zen; Raneem Albazaz; Prakash Manoharan; Stephen P Pereira; Richard Sturgess; Brian R Davidson; Hassan Z Malik; Derek Manas; Nigel Heaton; K Raj Prasad; John Bridgewater; Juan W Valle; Rebecca Goody; Maria Hawkins; Wendy Prentice; Helen Morement; Martine Walmsley; Shahid A Khan

doi:10.1136/gutjnl-2023-330029

British Society of Gastroenterology guidelines for the diagnosis and management of cholangiocarcinoma

Gut. 2023 Dec 7;73(1):16-46. doi: 10.1136/gutjnl-2023-330029.

Authors

Simon M Rushbrook¹, Timothy James Kendall^{2

3}, Yoh Zen⁴, Raneem Albazaz⁵, Prakash Manoharan⁶, Stephen P Pereira⁷, Richard Sturgess⁸, Brian R Davidson⁹, Hassan Z Malik¹⁰, Derek Manas¹¹, Nigel Heaton¹², K Raj Prasad¹³, John Bridgewater¹⁴, Juan W Valle¹⁵, Rebecca Goody¹⁶, Maria Hawkins¹⁷, Wendy Prentice¹⁸, Helen Morement¹⁹, Martine Walmsley²⁰, Shahid A Khan^{21

22}

Affiliations

¹ Department of Hepatology, Norfolk and Norwich University Hospitals NHS Trust, Norwich, UK.
² Division of Pathology, University of Edinburgh, Edinburgh, UK.
³ University of Edinburgh MRC Centre for Inflammation Research, Edinburgh, UK.
⁴ Department of Pathology, King's College London, London, UK.
⁵ Department of Radiology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
⁶ Department of Radiology, Christie Hospital, Manchester, UK.
⁷ GI Divison, University College London, London, UK.
⁸ Digestive Diseases Unit, Aintree University Hospitals NHS Foundation Trust, Liverpool, UK.
⁹ Department of Surgery, Royal Free Campus, UCL Medical School, London, UK.
¹⁰ Department of Surgery, University Hospital Aintree, Liverpool, UK.
¹¹ Department of Surgery, Newcastle University, Newcastle upon Tyne, Tyne and Wear, UK.
¹² Department of Hepatobiliary and Pancreatic Surgery, King's College London, London, UK.
¹³ John Goligher Colorectal Unit, St. James University Hospital, Leeds, UK.
¹⁴ Department of Oncology, UCL Cancer Institute, University College London, London, UK.
¹⁵ Department of Medical Oncology, The Christie NHS Foundation Trust/University of Manchester, Manchester, UK.
¹⁶ Department of Oncology, St James's University Hospital, Leeds, UK.
¹⁷ Department of Medical Physics and Biomedical Engineering, University College London, London, UK.
¹⁸ King's College Hospital NHS Foundation Trust, London, UK.
¹⁹ AMMF, Essex, UK.
²⁰ Chair of Trustees PSC Support, Didcot, UK.
²¹ Hepatology and Gastroenterology Section, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK [email protected].
²² Imperial College Healthcare NHS Trust, London, UK.

Abstract

These guidelines for the diagnosis and management of cholangiocarcinoma (CCA) were commissioned by the British Society of Gastroenterology liver section. The guideline writing committee included a multidisciplinary team of experts from various specialties involved in the management of CCA, as well as patient/public representatives from AMMF (the Cholangiocarcinoma Charity) and PSC Support. Quality of evidence is presented using the Appraisal of Guidelines for Research and Evaluation (AGREE II) format. The recommendations arising are to be used as guidance rather than as a strict protocol-based reference, as the management of patients with CCA is often complex and always requires individual patient-centred considerations.

Keywords: cholangiocarcinoma.

MeSH terms

Bile Duct Neoplasms* / diagnosis
Bile Duct Neoplasms* / therapy
Bile Ducts, Intrahepatic
Cholangiocarcinoma* / diagnosis
Cholangiocarcinoma* / therapy
Gastroenterology*
Humans