Portopulmonary hypertension: A focused review for the internist

Mamta S Chhabria; Leela Krishna Teja Boppana; Gaurav Manek; Adriano R Tonelli

doi:10.3949/ccjm.90a.23023

Portopulmonary hypertension: A focused review for the internist

Cleve Clin J Med. 2023 Oct 2;90(10):632-639. doi: 10.3949/ccjm.90a.23023.

Authors

Mamta S Chhabria¹, Leela Krishna Teja Boppana², Gaurav Manek¹, Adriano R Tonelli³

Affiliations

¹ Department of Pulmonary and Critical Care Medicine, Cleveland Clinic, Cleveland, OH.
² Department of Pulmonary and Critical Care Medicine, University of Florida College of Medicine, Jacksonville, FL.
³ Department of Pulmonary and Critical Care Medicine, and Director, Pulmonary Hemodynamic Laboratory, Cleveland Clinic, Cleveland, OH [email protected].

PMID: 37783493
DOI: 10.3949/ccjm.90a.23023

Abstract

Portopulmonary hypertension, ie, pulmonary arterial hypertension in a patient with portal hypertension, affects transplant eligibility and has a poor prognosis. The pathogenesis remains an area of active research, with various mechanisms proposed. Diagnosing it requires a detailed history, physical examination, laboratory tests, and echocardiographic evaluation, followed by a careful hemodynamic assessment.

Publication types

Review

MeSH terms

Echocardiography
Hemodynamics
Humans
Hypertension, Portal* / complications
Hypertension, Portal* / diagnosis
Hypertension, Pulmonary* / diagnosis
Hypertension, Pulmonary* / etiology
Pulmonary Arterial Hypertension* / complications