Essential Role of Endothelial Sphingolipid Biosynthesis in Cerebrovascular Homeostasis

Circ Res. 2023 Oct 27;133(10):880-882. doi: 10.1161/CIRCRESAHA.123.323183. Epub 2023 Oct 4.

Authors

Luisa Rubinelli^{1

2}, Lidia Garcia-Bonilla², Linda Sasset^{1

2}, Anna Cantalupo^{1

2}, Benjamin Goya², James E Ip³, Josef Anrather², Costantino Iadecola², Giuseppe Faraco², Annarita Di Lorenzo^{1

2}

Affiliations

¹ Department of Pathology and Laboratory Medicine, Cardiovascular Research Institute (L.R., L.S., A.C., A.D.L.), Weill Cornell Medicine, New York, NY.
² Feil Family Brain and Mind Research Institute (L.R., L.G.-B., L.S., A.C., B.G., J.A., C.I., G.F., A.D.L.), Weill Cornell Medicine, New York, NY.
³ Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York Presbyterian Hospital (J.E.I.).

No abstract available

Keywords: blood-brain barrier; cerebrovascular circulation; endothelial cells; sphingolipids.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Homeostasis
Lipogenesis*
Sphingolipids*

Substances

Sphingolipids

Grants and funding