The present study examined the intergenerational transmission of economic adversity, as well as physical and mental health across generations. Specifically, we examined the effects of parental economic adversity, body mass index (BMI), and emotional distress during the child's adolescence on their economic adversity, BMI, and emotional distress in middle adulthood. The study included 366 Generation 1 (G1) mothers and fathers and their adolescents (Generation 2; G2) in middle adulthood. G1 behavior was examined when G2 was 16 years old and G2 behavior was assessed at Age 42. In line with aspects of the family stress model, economic hardship was related to economic pressure, which in turn was related to emotional distress for both G1 and G2. For each generation, economic pressure was also associated with BMI. There was also evidence of the intergenerational transmission of economic hardship, BMI, and emotional distress from G1 to G2. Finally, the intergenerational transmission of economic adversity in the family of origin to adult health outcomes was explained by these same health behaviors of the first generation. Results suggest that economic adversity and parental health behaviors as experienced in adolescence have long-term economic and health consequences into middle adulthood. (PsycInfo Database Record (c) 2023 APA, all rights reserved).