Complex chromosomal rearrangement and multiple spontaneous abortions

Hum Genet. 1986 Nov;74(3):326. doi: 10.1007/BF00282560.

Abstract

We report on a woman with a balanced complex chromosomal rearrangement (CCR) involving chromosomes 7, 10, and 21. She is the third individual with an apparently de novo CCR to be ascertained by repeated fetal wastage. Both familial and de novo CCRs are associated with recurrent spontaneous abortions.

Publication types

  • Case Reports

MeSH terms

  • Abortion, Habitual / etiology
  • Abortion, Habitual / genetics*
  • Adult
  • Chromosome Aberrations / complications
  • Chromosome Aberrations / genetics*
  • Chromosome Disorders
  • Chromosomes, Human, Pair 10 / ultrastructure*
  • Chromosomes, Human, Pair 21 / ultrastructure*
  • Chromosomes, Human, Pair 7 / ultrastructure*
  • Female
  • Humans
  • Pregnancy
  • Translocation, Genetic*