Acquired plasminogen deficiency and ligneous conjunctivitis associated with chronic tranexamic acid use

Lancet Haematol. 2023 Dec;10(12):e1016. doi: 10.1016/S2352-3026(23)00247-8. Epub 2023 Oct 19.

Authors

John R Leister¹, Scott T McEwen², Vania Rashidi³, Wassef Chanbour³, Alexander A Boucher⁴

Affiliations

¹ Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, USA. Electronic address: [email protected].
² Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, USA.
³ Department of Ophthalmology and Visual Neurosciences, University of Minnesota Medical School, Minneapolis, MN, USA.
⁴ Departments of Pediatrics and Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.

PMID: 37866375
DOI: 10.1016/S2352-3026(23)00247-8

No abstract available

MeSH terms

Coagulation Protein Disorders
Conjunctivitis* / drug therapy
Conjunctivitis* / etiology
Humans
Plasminogen / deficiency
Skin Diseases, Genetic* / drug therapy
Tranexamic Acid* / adverse effects

Substances

Tranexamic Acid
Plasminogen

Supplementary concepts

Plasminogen Deficiency, Type I
Congenital Plasminogen Deficiency