The good, the bald, and the hairy: A mechanosensor meets its fate at the target

Christopher D Deppmann; Eli R Zunder

doi:10.1016/j.devcel.2023.08.027

The good, the bald, and the hairy: A mechanosensor meets its fate at the target

Dev Cell. 2023 Oct 23;58(20):2013-2014. doi: 10.1016/j.devcel.2023.08.027.

Authors

Christopher D Deppmann¹, Eli R Zunder²

Affiliations

¹ Department of Biology, College of Arts and Sciences, Charlottesville, VA 22902, USA; Neuroscience Graduate Program, School of Medicine, University of Virginia, Charlottesville, VA 229022, USA; Department of Biomedical Engineering, School of Engineering, University of Virginia, Charlottesville, VA 22902, USA; Department of Neuroscience, School of Medicine, University of Virginia, Charlottesville, VA 229022, USA; Department of Cell Biology, School of Medicine, University of Virginia, Charlottesville, VA 229022, USA; Program in Fundamental Neuroscience, College of Arts and Sciences, Charlottesville, VA 22902, USA. Electronic address: [email protected].
² Neuroscience Graduate Program, School of Medicine, University of Virginia, Charlottesville, VA 229022, USA; Department of Biomedical Engineering, School of Engineering, University of Virginia, Charlottesville, VA 22902, USA. Electronic address: [email protected].

PMID: 37875070
DOI: 10.1016/j.devcel.2023.08.027

Abstract

In this issue of Developmental Cell, Koutsioumpa et al. (2023) investigate the maturation of low-threshold mechanoreceptor nerve endings in both hairy and glabrous skin types and discover a critical role for target-derived BMP in the development of Meissner corpuscles in glabrous (i.e., hairless) skin.

Publication types

Comment

MeSH terms

Hair*
Mechanoreceptors / metabolism
Skin* / innervation