In 2022, the United Kingdom reported an increase in drug resistance in Shigella sonnei isolates. We report 33 cases in Spain genetically related to the UK cases and 4 cases with similar antimicrobial resistance profiles infected with genetically distant strains. Our results suggest circulation of multiple genetic clusters of multidrug-resistant S. sonnei in Spain.
Keywords: Shigella sonnei; Spain; XDR; antimicrobial resistance; bacteria; drug resistance; extensively drug-resistant; infections; sexual transmission.