When age is not an obstacle: A case series of endoscopic transsphenoidal resection of pituitary macroadenomas in older patients

Biomed Rep. 2023 Oct 3;19(5):86. doi: 10.3892/br.2023.1668. eCollection 2023 Nov.

Abstract

Due to the increase in life expectancy, the number of elderly patients suffering from a pituitary macroadenoma is expected to increase in the future. The endoscopic endonasal transsphenoidal (EET) approach tends to be the first choice for the treatment of pituitary macroadenomas in the general population. Notwithstanding, in the geriatric population, the goals of management for this condition remain unclear. The present study retrospectively evaluated and describes the cases of 6 patients >70 years of age with a pituitary macroadenoma who were treated by a skull base team, composed of one ENT surgeon and one neurosurgeon. All the patients experienced a notable improvement in their neurological deficit, while their hormonal status also improved or at least did not deteriorate after the surgery. The EET approach appears to be a safe and effective approach for the treatment of pituitary macroadenomas in the geriatric population.

Keywords: elderly; endoscopic endonasal transsphenoidal approach; geriatric population; pituitary macroadenomas; surgery.

Publication types

  • Case Reports

Grants and funding

Funding: No funding was received.