CD19/CD22 dual-targeting chimeric antigen receptor T-cell therapy bridging to allogeneic haematopoietic stem cell transplantation for B-cell acute lymphoblastic leukaemia delays platelet recovery and increases risks of cytomegalovirus and Epstein-Barr virus viremia after transplantation

Shijia Li; Jianrong Ge; Shiyuan Zhou; Wenjuan Zhu; Yue Han; Suning Chen; Shengli Xue; Ying Wang; Huiying Qiu; Xiaojin Wu; Depei Wu

doi:10.1002/ctm2.1459

CD19/CD22 dual-targeting chimeric antigen receptor T-cell therapy bridging to allogeneic haematopoietic stem cell transplantation for B-cell acute lymphoblastic leukaemia delays platelet recovery and increases risks of cytomegalovirus and Epstein-Barr virus viremia after transplantation

Clin Transl Med. 2023 Oct;13(10):e1459. doi: 10.1002/ctm2.1459.

Authors

Shijia Li^{1

2}, Jianrong Ge¹, Shiyuan Zhou^{1

2}, Wenjuan Zhu^{1

2}, Yue Han^{1

2}, Suning Chen^{1

2}, Shengli Xue^{1

2}, Ying Wang^{1

2}, Huiying Qiu^{1

2}, Xiaojin Wu^{1

2}, Depei Wu^{1

2}

Affiliations

¹ National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
² Collaborative Innovation Center of Hematology, Institute of Blood and Marrow Transplantation, Soochow University, Suzhou, China.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Cytomegalovirus
Epstein-Barr Virus Infections*
Hematopoietic Stem Cell Transplantation* / adverse effects
Herpesvirus 4, Human
Humans
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma*
Receptors, Chimeric Antigen* / genetics
Sialic Acid Binding Ig-like Lectin 2
Viremia

Substances

Receptors, Chimeric Antigen
CD22 protein, human
Sialic Acid Binding Ig-like Lectin 2