1 Vascular Medicine and Biology Theme, Biosciences Institute, Newcastle University, International Centre for Life, Times Square, Newcastle upon Tyne, NE1 4EP, UK.
2 Peter-Osypka Heart Centre Munich, Internistisches Klinikum München Süd, Am Isarkanal 36, 81379 München, Munich, Germany.
3 Technical University of Munich, Arcisstraße 21, 80333 München, Munich, Germany.
4 Department of Cardiology, The Newcastle Upon Tyne Hospitals NHS Foundation Trust, Freeman Hospital, Freeman Rd, High Heaton, Newcastle upon Tyne, NE7 7DN, UK.