Subacute infective endocarditis due to Lodderomyces elongisporus: a case report and review of the literature

Front Public Health. 2023 Oct 20:11:1181377. doi: 10.3389/fpubh.2023.1181377. eCollection 2023.

Abstract

Lodderomyces elongisporus, a rare emerging pathogen, can cause fungemia often related to immunosuppression or intravenous devices. Herein, we report the case of a 58-year-old woman with subacute infective endocarditis due to Lodderomyces elongisporus identified by blood fungal culture and whole-genome sequencing, who was treated with antifungals, mitral replacement and endocardial vegetation removal surgery.

Keywords: Lodderomyces elongisporus; central nervous system infection; fungemia; infective endocarditis; invasive fungal disease.

Publication types

  • Review
  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antifungal Agents / therapeutic use
  • Endocarditis* / diagnosis
  • Endocarditis* / drug therapy
  • Endocarditis* / microbiology
  • Female
  • Humans
  • Middle Aged
  • Saccharomycetales* / genetics

Substances

  • Antifungal Agents

Supplementary concepts

  • Lodderomyces elongisporus

Grants and funding

This study was supported by grants from the National Natural Science Foundation of China [grant numbers NSFC 82202544 and Science and Technology Program of Guangzhou (202201020537)].