Discovering how the amygdala shapes human behavior: From lesion studies to neuromodulation

Neuron. 2023 Dec 20;111(24):3906-3910. doi: 10.1016/j.neuron.2023.09.040. Epub 2023 Nov 7.

Abstract

Case studies of patients with amygdala damage or those receiving direct amygdala stimulation have informed our understanding of the amygdala's role in emotion and cognition. These foundational studies illustrate how the human amygdala influences our present behavior and prioritizes memories of our past in service of future experiences. This broad influence makes the amygdala a novel target for clinical neuromodulation.

MeSH terms

  • Amygdala* / physiology
  • Cognition
  • Emotions* / physiology
  • Humans