MRI brain findings of Abamectin toxic encephalopathy: a case report with review of literature

Emerg Radiol. 2023 Dec;30(6):817-821. doi: 10.1007/s10140-023-02180-3. Epub 2023 Nov 10.

Abstract

Abamectin is an insecticidal/miticidal compound derived from the soil bacterium "Streptomyces avermitilis". Abamectin toxicity in humans is very rare. We present a case of acute neurotoxicity induced by Abamectin, showcasing distinctive MRI brain findings in a 33-year-old female who exhibited a favourable recovery with the aid of supportive care. In a patient with known exposure to toxins, even with a lack of knowledge of the specific type or class of toxin, recognition of anatomical distribution of lesions on brain MRI and their characteristic appearance can help exclude other causes of neurologic impairment and aid in timely management.

Keywords: Abamectin; Acute poisoning; Encephalopathy; MRI; Toxic.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Adult
  • Brain / diagnostic imaging
  • Female
  • Humans
  • Ivermectin* / toxicity
  • Magnetic Resonance Imaging
  • Neurotoxicity Syndromes* / diagnostic imaging
  • Neurotoxicity Syndromes* / etiology

Substances

  • abamectin
  • Ivermectin