Intravascular Imaging-Derived Physiology-Basic Principles and Clinical Application

Annemieke C Ziedses des Plantes; Alessandra Scoccia; Frank Gijsen; Gijs van Soest; Joost Daemen

doi:10.1016/j.ccl.2023.07.005

Intravascular Imaging-Derived Physiology-Basic Principles and Clinical Application

Cardiol Clin. 2024 Feb;42(1):89-100. doi: 10.1016/j.ccl.2023.07.005.

Authors

Annemieke C Ziedses des Plantes¹, Alessandra Scoccia¹, Frank Gijsen², Gijs van Soest², Joost Daemen³

Affiliations

¹ Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, the Netherlands.
² Department of Biomedical Engineering, Erasmus University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, the Netherlands.
³ Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, the Netherlands. Electronic address: [email protected].

PMID: 37949542
DOI: 10.1016/j.ccl.2023.07.005

Abstract

Intravascular imaging-derived physiology is emerging as a promising tool allowing simultaneous anatomic and functional lesion assessment. Recently, several optical coherence tomography-based and intravascular ultrasound-based fractional flow reserve (FFR) indices have been developed that compute FFR through computational fluid dynamics, fluid dynamics equations, or machine-learning methods. This review aims to provide an overview of the currently available intravascular imaging-based physiologic indices, their diagnostic performance, and clinical application.

Keywords: Functional lesion assessment; IVUS-based FFR; OCT-based FFR; OFR; Percutaneous coronary intervention; Virtual FFR.

Publication types

Review

MeSH terms

Coronary Angiography
Coronary Vessels / diagnostic imaging
Fractional Flow Reserve, Myocardial* / physiology
Humans
Predictive Value of Tests
Severity of Illness Index
Tomography, Optical Coherence / methods
Ultrasonography, Interventional / methods