Where Artificial Intelligence Can Take Us in the Management and Understanding of Cancerization Fields

Cancers (Basel). 2023 Nov 2;15(21):5264. doi: 10.3390/cancers15215264.

Abstract

Squamous cell carcinoma and its precursor lesion actinic keratosis are often found together in areas of skin chronically exposed to sun, otherwise called cancerisation fields. The clinical assessment of cancerisation fields and the correct diagnosis of lesions within these fields is usually challenging for dermatologists. The recent adoption of skin cancer diagnostic imaging techniques, particularly LC-OCT, helps clinicians in guiding treatment decisions of cancerization fields in a non-invasive way. The combination of artificial intelligence and non-invasive skin imaging opens up many possibilities as AI can perform tasks impossible for humans in a reasonable amount of time. In this text we review past examples of the application of AI to dermatological images for actinic keratosis/squamous cell carcinoma diagnosis, and we discuss about the prospects of the application of AI for the characterization and management of cancerization fields.

Keywords: LC-OCT; actinic keratosis; artificial intelligence; cancerization field; line-field confocal optical coherence tomography; non-invasive imaging; squamous cell carcinoma.

Grants and funding

This research received no external funding.