Characterization of reverse-engineered anti-PF4 stereotypic antibodies derived from serum of patients with VITT

Blood. 2024 Jan 25;143(4):370-374. doi: 10.1182/blood.2023021307.

Jing Jing Wang^{1

2}, Marijn van der Neut Kolfschoten³, Lucy Rutten³, Bridie Armour^{1

2}, Chee Wee Tan^{4

5

6}, Tim Chataway⁷, Rinke Bos³, Annemart Koornneef³, Pravien Abeywickrema⁸, Rick Kapur⁹, Leendert Porcelijn¹⁰, Midia Khalifa³, Ava Sadi³, Pascale Bouchier³, Eleni Kourkouta³, Aditya Perkasa³, Ted Kwaks³, Roland Zahn³, Laura Solforosi³, Tom P Gordon^{1

2}

¹ Department of Immunology, College of Medicine and Public Health, Flinders University, Bedford Park, SA, Australia.
² Department of Immunology, SA Pathology, Flinders Medical Centre, Bedford Park, SA, Australia.
³ Janssen Vaccines & Prevention B.V., Leiden, The Netherlands.
⁴ Department of Medicine, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia.
⁵ Department of Hematology, SA Pathology, Adelaide, SA, Australia.
⁶ Department of Hematology, Royal Adelaide Hospital, Central Area Local Health Network, Adelaide, SA, Australia.
⁷ Flinders Proteomics Facility, College of Medicine and Public Health, Flinders University, Bedford Park, SA, Australia.
⁸ Structural & Protein Sciences, Janssen Research and Development, Spring House, PA.
⁹ Sanquin Research, Department of Experimental Immunohematology, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
¹⁰ Department of Immunohematology Diagnostics, Sanquin Diagnostic Services, Amsterdam, The Netherlands.

No abstract available

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