Natural variants of molybdate transporters contribute to yield traits of soybean by affecting auxin synthesis

Curr Biol. 2023 Dec 18;33(24):5355-5367.e5. doi: 10.1016/j.cub.2023.10.072. Epub 2023 Nov 22.

Abstract

Soybean (Glycine max) is a crop with high demand for molybdenum (Mo) and typically requires Mo fertilization to achieve maximum yield potential. However, the genetic basis underlying the natural variation of Mo concentration in soybean and its impact on soybean agronomic performance is still poorly understood. Here, we performed a genome-wide association study (GWAS) to identify GmMOT1.1 and GmMOT1.2 that drive the natural variation of soybean Mo concentration and confer agronomic traits by affecting auxin synthesis. The soybean population exhibits five haplotypes of the two genes, with the haplotype 5 demonstrating the highest expression of GmMOT1.1 and GmMOT1.2, as well as the highest transport activities of their proteins. Further studies showed that GmMOT1.1 and GmMOT1.2 improve soybean yield, especially when cultivated in acidic or slightly acidic soil. Surprisingly, these two genes contribute to soybean growth by enhancing the activity of indole-3-acetaldehyde (IAAld) aldehyde oxidase (AO), leading to increased indole-3-acetic acid (IAA) synthesis, rather than being involved in symbiotic nitrogen fixation or nitrogen assimilation. Furthermore, the geographical distribution of five haplotypes in China and their correlation with soil pH suggest the potential significance of GmMOT1.1 and GmMOT1.2 in soybean breeding strategies.

Keywords: aldehyde oxidase; auxin; molybdate transporter; molybdenum; natural variation; soil pH; soybean.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Genome-Wide Association Study
  • Glycine max* / genetics
  • Indoleacetic Acids / metabolism
  • Molybdenum* / metabolism
  • Plant Breeding
  • Soil

Substances

  • molybdate
  • Molybdenum
  • Indoleacetic Acids
  • Soil