Comments on "Overview and thermodynamic modelling of deep eutectic solvents as co-solvents to enhance drug solubilities in water"

Raha Kaviani; Ali Shayanfar

doi:10.1016/j.ejpb.2023.11.018

Comments on "Overview and thermodynamic modelling of deep eutectic solvents as co-solvents to enhance drug solubilities in water"

Eur J Pharm Biopharm. 2023 Dec:193:306-307. doi: 10.1016/j.ejpb.2023.11.018. Epub 2023 Nov 23.

Authors

Raha Kaviani¹, Ali Shayanfar²

Affiliations

¹ Student Research Committee, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
² Pharmaceutical Analysis Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: [email protected].

PMID: 38000516
DOI: 10.1016/j.ejpb.2023.11.018

Abstract

This communication highlights the significance of the final pH of the solution and the potential instability of deep eutectic solvent (DES) within aqueous solutions, and introducing a challenging aspect regarding solute solubilization by DESs.

Keywords: Deep eutectic solvents; Solubility; Thermodynamic modelling.

Publication types

Letter

MeSH terms

Deep Eutectic Solvents*
Solubility
Solvents
Thermodynamics
Water*

Substances

Solvents
Water
Deep Eutectic Solvents