Imaging and Stereotactic Electroencephalography Functional Networks to Guide Epilepsy Surgery

Neurosurg Clin N Am. 2024 Jan;35(1):61-72. doi: 10.1016/j.nec.2023.09.001. Epub 2023 Sep 23.

Abstract

Epilepsy surgery is a potentially curative treatment of drug-resistant epilepsy that has remained underutilized both due to inadequate referrals and incomplete localization hypotheses. The complexity of patients evaluated for epilepsy surgery has increased, thus new approaches are necessary to treat these patients. The paradigm of epilepsy surgery has evolved to match this challenge, now considering the entire seizure network with the goal of disrupting it through resection, ablation, neuromodulation, or a combination. The network paradigm has the potential to aid in identification of the seizure network as well as treatment selection.

Keywords: Connectivity; Connectomics; DTI; Epilepsy surgery; SEEG; fMRI; iEEG.

Publication types

  • Review

MeSH terms

  • Brain Mapping / methods
  • Drug Resistant Epilepsy* / diagnostic imaging
  • Drug Resistant Epilepsy* / surgery
  • Electroencephalography / methods
  • Epilepsy* / diagnostic imaging
  • Epilepsy* / surgery
  • Humans
  • Seizures / surgery
  • Stereotaxic Techniques
  • Treatment Outcome