Imaging Modalities for Evaluating Lymphedema

Medicina (Kaunas). 2023 Nov 16;59(11):2016. doi: 10.3390/medicina59112016.

Abstract

Lymphedema is a progressive condition. Its therapy aims to reduce edema, prevent its progression, and provide psychosocial aid. Nonsurgical treatment in advanced stages is mostly insufficient. Therefore-in many cases-surgical procedures, such as to restore lymph flow or excise lymphedema tissues, are the only ways to improve patients' quality of life. Imaging modalities: Lymphoscintigraphy (LS), near-infrared fluorescent (NIRF) imaging-also termed indocyanine green (ICG) lymphography (ICG-L)-ultrasonography (US), magnetic resonance lymphangiography (MRL), computed tomography (CT), photoacoustic imaging (PAI), and optical coherence tomography (OCT) are standardized techniques, which can be utilized in lymphedema diagnosis, staging, treatment, and follow-up. Conclusions: The combined use of these imaging modalities and self-assessment questionnaires deliver objective parameters for choosing the most suitable surgical therapy and achieving the best possible postoperative outcome.

Keywords: computed tomography (CT); indocyanine green (ICG); lymphedema; lympho-venous anastomosis (LVA); lymphoscintigraphy (LS); magnetic resonance lymphangiography (MRL); near-infrared fluorescent (NIRF) imaging; optical coherence tomography (OCT); photoacoustic imaging (PAI); ultrasonography (US).

Publication types

  • Review

MeSH terms

  • Coloring Agents
  • Humans
  • Indocyanine Green
  • Lymphedema* / surgery
  • Lymphedema* / therapy
  • Lymphography / methods
  • Quality of Life*

Substances

  • Indocyanine Green
  • Coloring Agents

Grants and funding

This research received no external funding.