Loss of Muscle Mass and Strength After Hip Fracture: an Intervention Target for Nutrition Supplementation

Curr Osteoporos Rep. 2023 Dec;21(6):710-718. doi: 10.1007/s11914-023-00836-0. Epub 2023 Nov 29.

Abstract

Purposeof review: To summarize what is known about the deleterious effect of hip fracture on muscle mass and strength as well as the scientific evidence for post-surgical nutrition supplementation to maintain muscle and improve function.

Recent findings: This review provides a discussion of the relationship between muscle mass, strength, and physical function following hip fracture, briefly describes the approaches to measuring lean mass, discusses prevalence of sarcopenia and malnutrition among older men and women with hip fracture, and reviews the effects of essential amino acids on muscle. Loss of muscle mass and strength following hip fracture is substantial with consequences for recovery of functional independence. EAA-based nutrition supplementation, which directly effects muscle, has potential to improve outcomes.

Keywords: Essential amino acids; Hip fracture; Muscle mass; Muscle strength; Physical function; Sarcopenia.

Publication types

  • Review

MeSH terms

  • Aged
  • Dietary Supplements
  • Female
  • Hip Fractures* / epidemiology
  • Humans
  • Male
  • Muscle Strength / physiology
  • Muscles
  • Physical Therapy Modalities
  • Sarcopenia*