Tc-99m MDP Scan with Unusual and Isolated Skeletal Metastasis in Skull Bone in a Case of Testicular Seminoma

Indian J Nucl Med. 2023 Jul-Sep;38(3):289-291. doi: 10.4103/ijnm.ijnm_197_22. Epub 2023 Oct 10.

Abstract

Seminomas are common germ cell tumors (GCT) that may arise in the testes as well as in extra testicular locations such as mediastinum with/without testicular tumor. Testicular tumors are usually detected early due to their location and presentation as testicular mass. The overall prognosis of the seminomatous GCTs is good with surgery as the mainstay of treatment in localized disease. Bone metastases, especially when present in isolation are exceedingly rare in seminoma. Here, we present a rare case of skull bone metastasis in a case of testicular seminoma which was detected on technetium-99m labeled methylene diphosphonate bone scintigraphy with single-photon emission computed tomography with computed tomography.

Keywords: Bone metastasis; isolated skull metastasis; seminoma; single-photon emission computed tomography with computed tomography; technetium-99m labeled methylene diphosphonate scan.