Evaluation of the Xpert Xpress GBS test for rapid detection of group B Streptococcus in pregnant women

Microbiol Spectr. 2024 Jan 11;12(1):e0220623. doi: 10.1128/spectrum.02206-23. Epub 2023 Dec 6.

Abstract

This was the first study evaluating the performance of the Xpert Xpress group B Streptococcus (GBS) test using rectovaginal swabs from Chinese pregnant women. Compared to the other three assays, the Xpert Xpress GBS test demonstrated high sensitivity and specificity when screening 939 pregnant women for GBS in rectovaginal specimens. Additionally, its reduced time to obtain results makes it valuable for the rapid detection of GBS.

Keywords: Xpert Xpress GBS; direct culture; enrichment culture; group B Streptococcus; qPCR.

MeSH terms

  • Female
  • Humans
  • Pregnancy
  • Pregnancy Complications, Infectious* / diagnosis
  • Pregnant Women
  • Streptococcal Infections* / diagnosis
  • Streptococcus agalactiae / genetics
  • Vagina