T-lymphocyte tumors are a group of diseases containing various types of lymphatic system tumors, with strong heterogeneity and poor clinical outcomes. Chimeric antigen receptor T (CAR-T) cell therapy, as a new immune cell therapy, has made a breakthrough in the field of B-lymphocyte tumors. People are interested in the application prospect of this technique in the field of T-lymphocyte tumors. Some studies have shown that CAR-T cell therapy has made some progress in the treatment of T-lymphocyte tumors, and CAR-T for some targets has entered the stage of clinical trials. However, due to the characteristics of T cells, there are also many challenges. This article reviews the research and application of CAR-T cell therapy in T-lymphocyte tumors.
题目: 应用CAR-T细胞治疗T淋巴细胞肿瘤的最新研究进展.
摘要: T淋巴细胞肿瘤是一组包含多种类型的淋巴系统肿瘤的疾病，异质性强，临床转归差。嵌合抗原受体T细胞（CAR-T）疗法作为一种新的免疫细胞治疗方式，在B淋巴细胞肿瘤领域取得了突破性进展，据此，人们对这项技术在T淋巴细胞肿瘤领域的应用前景也产生了浓厚的兴趣。研究表明，CAR-T细胞治疗T淋巴细胞肿瘤已经取得了一定进展，针对某些靶点的CAR-T已经进入临床试验阶段。但是由于T细胞本身的特性，目前也存在很多挑战。本文对于应用CAR-T细胞治疗T淋巴细胞肿瘤的最新研究进展作一综述。.
Keywords: CAR-T cell therapy; T-lymphocyte tumors; challenge; progress.