Abstract
Antibodies on mucosal surfaces of the upper respiratory tract have been shown to be important for protection from infection with SARS-CoV-2. Here we investigate the induction of serum IgG, saliva IgG, and saliva sIgA after COVID-19 mRNA booster vaccination or breakthrough infections.
Keywords:
SARS-CoV-2; booster vaccination; breakthrough infection; mRNA vaccine; sIgA; saliva; spike.
MeSH terms
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Adult
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Antibodies, Viral* / blood
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Antibodies, Viral* / immunology
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Antibody Formation / immunology
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Breakthrough Infections
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COVID-19 Vaccines* / administration & dosage
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COVID-19 Vaccines* / immunology
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COVID-19* / immunology
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COVID-19* / prevention & control
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Female
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Humans
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Immunity, Mucosal*
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Immunization, Secondary*
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Immunoglobulin A, Secretory / immunology
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Immunoglobulin G* / blood
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Immunoglobulin G* / immunology
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Male
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Middle Aged
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SARS-CoV-2* / immunology
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Saliva* / immunology
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Vaccination
Substances
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Antibodies, Viral
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COVID-19 Vaccines
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Immunoglobulin G
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Immunoglobulin A, Secretory
Supplementary concepts
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COVID-19 breakthrough infections