Eliminating Health Disparities in Atrial Fibrillation, Heart Failure, and Dyslipidemia: A Path Toward Achieving Pharmacoequity

Curr Atheroscler Rep. 2023 Dec;25(12):1113-1127. doi: 10.1007/s11883-023-01180-5. Epub 2023 Dec 18.

Abstract

Purpose of review: Pharmacoequity refers to the goal of ensuring that all patients have access to high-quality medications, regardless of their race, ethnicity, gender, or other characteristics. The goal of this article is to review current evidence on disparities in access to cardiovascular drug therapies across sociodemographic subgroups, with a focus on heart failure, atrial fibrillation, and dyslipidemia.

Recent findings: Considerable and consistent disparities to life-prolonging heart failure, atrial fibrillation, and dyslipidemia medications exist in clinical trial representation, access to specialist care, prescription of guideline-based therapy, drug affordability, and pharmacy accessibility across racial, ethnic, gender, and other sociodemographic subgroups. Researchers, health systems, and policy makers can take steps to improve pharmacoequity by diversifying clinical trial enrollment, increasing access to inpatient and outpatient cardiology care, nudging clinicians to increase prescription of guideline-directed medical therapy, and pursuing system-level reforms to improve drug access and affordability.

Keywords: Atrial fibrillation; Diversity; Dyslipidemia; Heart failure; Pharmacoequity.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't
  • Research Support, N.I.H., Extramural

MeSH terms

  • Atrial Fibrillation* / drug therapy
  • Dyslipidemias* / drug therapy
  • Dyslipidemias* / epidemiology
  • Ethnicity
  • Health Inequities
  • Heart Failure* / drug therapy
  • Humans