Recent advances in copper sulfide nanoparticles for phototherapy of bacterial infections and cancer

Nanomedicine (Lond). 2023 Dec;18(30):2185-2204. doi: 10.2217/nnm-2023-0202. Epub 2023 Dec 20.

Abstract

Copper sulfide nanoparticles (CuS NPs) have attracted growing interest in biomedical research due to their remarkable properties, such as their high photothermal and thermodynamic capabilities, which are ideal for anticancer and antibacterial applications. This comprehensive review focuses on the current state of antitumor and antibacterial applications of CuS NPs. The initial section provides an overview of the various approaches to synthesizing CuS NPs, highlighting the size, shape and composition of CuS NPs fabricated using different methods. In this review, the mechanisms underlying the antitumor and antibacterial activities of CuS NPs in medical applications are discussed and the clinical challenges associated with the use of CuS NPs are also addressed.

Keywords: antibacterial; anticancer; copper sulfide nanoparticles; photodynamic therapy; photothermal therapy.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Bacterial Infections* / drug therapy
  • Copper / therapeutic use
  • Humans
  • Nanoparticles* / therapeutic use
  • Neoplasms* / drug therapy
  • Phototherapy
  • Sulfides / therapeutic use

Substances

  • Copper
  • Sulfides
  • Anti-Bacterial Agents