Infective endocarditis and septic arthritis caused by Corynebacteriumstriatum

J Infect Chemother. 2024 Jul;30(7):655-658. doi: 10.1016/j.jiac.2023.12.009. Epub 2023 Dec 22.

Abstract

Corynebacterium striatum occasionally causes nosocomial infections, such as catheter-related bloodstream infection and pneumonia; however, C. striatum-related infective endocarditis or septic arthritis is uncommon. We present the case of an 85-year-old woman with infective endocarditis at the native valve and septic arthritis at the native shoulder joint caused by C. striatum. The patient was admitted for a 10-day history of fever and right shoulder pain. She had no history of artificial device implantation, injury, arthrocentesis, or hospitalization. A physical examination revealed conjunctival petechiae, a systolic heart murmur, and right shoulder joint swelling. C. striatum was observed in two blood culture sets. Transesophageal echocardiography revealed vegetation in the right aortic coronary cusp. Arthrocentesis at the right shoulder aspirated pyogenic fluid and C. striatum was detected in the culture. The patient was diagnosed with infective endocarditis and septic arthritis caused by C. striatum, and ampicillin was administered based on antimicrobial susceptibility test results. The patient's condition was initially stable; however, she developed pulmonary congestion on day 56 and eventually died. An autopsy demonstrated perforation of the aortic left coronary cusp with vegetation. C. striatum may cause native valve endocarditis and native joint septic arthritis.

Keywords: Ampicillin; Corynebacterium striatum; Infective endocarditis; Native joint; Native valve; Septic arthritis.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use
  • Aortic Valve / diagnostic imaging
  • Aortic Valve / microbiology
  • Aortic Valve / pathology
  • Arthritis, Infectious* / diagnosis
  • Arthritis, Infectious* / drug therapy
  • Arthritis, Infectious* / microbiology
  • Corynebacterium Infections* / complications
  • Corynebacterium Infections* / diagnosis
  • Corynebacterium Infections* / drug therapy
  • Corynebacterium Infections* / microbiology
  • Corynebacterium* / isolation & purification
  • Echocardiography, Transesophageal
  • Endocarditis, Bacterial* / complications
  • Endocarditis, Bacterial* / diagnosis
  • Endocarditis, Bacterial* / drug therapy
  • Endocarditis, Bacterial* / microbiology
  • Fatal Outcome
  • Female
  • Humans

Substances

  • Anti-Bacterial Agents

Supplementary concepts

  • Corynebacterium striatum