RNA is a central molecule in the life cycle of viruses, acting not only as messenger (m)RNA but also as a genome. Given these critical roles, it is not surprising that viral RNA is a hub for host-virus interactions. However, the interactome of viral RNAs remains largely unknown. This chapter discusses the importance of cellular RNA-binding proteins in virus infection and the emergent approaches developed to uncover and characterise them.
Keywords: Interferon-Stimulated Genes (ISGs); RNA; RNA Interactome Capture (RIC); RNA viruses; RNA-Binding Proteins (RBPs); Riboregulation.
© 2023. The Author(s), under exclusive license to Springer Nature Switzerland AG.