Acute myeloid leukemia stratifies as 2 clinically relevant sphingolipidomic subtypes
Blood Adv
.
2024 Mar 12;8(5):1137-1142.
doi: 10.1182/bloodadvances.2023010535.
Authors
B Bishal Paudel
1
,
Su-Fern Tan
2
,
Todd E Fox
3
,
Johnson Ung
2
4
,
Upendarrao Golla
5
,
Jeremy J P Shaw
2
,
Wendy Dunton
2
,
Irene Lee
2
6
,
Wisam A Fares
1
,
Satyam Patel
7
,
Arati Sharma
7
8
,
Aaron D Viny
9
10
,
Brian M Barth
11
12
,
Martin S Tallman
13
,
Myles Cabot
14
15
,
Francine E Garrett-Bakelman
2
16
17
,
Ross L Levine
18
19
,
Mark Kester
3
,
David J Feith
2
17
,
David Claxton
5
8
,
Kevin A Janes
1
16
17
,
Thomas P Loughran Jr
2
17
Affiliations
1
Department of Biomedical Engineering, University of Virginia, Charlottesville, VA.
2
Department of Medicine, Division of Hematology & Oncology, University of Virginia, Charlottesville, VA.
3
Department of Pharmacology, University of Virginia, Charlottesville, VA.
4
Department of Microbiology/Immunology/Cancer Biology, University of Virginia, Charlottesville, VA.
5
Department of Medicine, Division of Hematology and Oncology, Pennsylvania State University College of Medicine, Hershey, PA.
6
Department of Internal Medicine, Baylor College of Medicine, Houston, TX.
7
Department of Pharmacology, Pennsylvania State University College of Medicine, Hershey, PA.
8
Penn State Cancer Institute, Hershey, PA.
9
Department of Medicine, Division of Hematology & Oncology, and of Genetics & Development, Herbert Irving Comprehensive Cancer Center, New York, NY.
10
Columbia Stem Cell Initiative, Columbia University Irving Medical Center, New York, NY.
11
Department of Chemistry, Biology, and Health Sciences, South Dakota School of Mines and Technology, Rapid City, SD.
12
Department of Natural Sciences, University of Alaska Southeast, Juneau, AK.
13
Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL.
14
Department of Biochemistry & Molecular Biology, East Carolina University, Greenville, NC.
15
East Carolina Diabetes and Obesity Institute, Brody School of Medicine, East Carolina University, Greenville, NC.
16
Department of Biochemistry & Molecular Genetics, University of Virginia, Charlottesville, VA.
17
University of Virginia Cancer Center, Charlottesville, VA.
18
Human Oncology and Pathogenesis Program and Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY.
19
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
PMID:
38170742
PMCID:
PMC10909712
DOI:
10.1182/bloodadvances.2023010535
No abstract available
Publication types
Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural
MeSH terms
Humans
Leukemia, Myeloid, Acute* / diagnosis
Nucleophosmin
Substances
Nucleophosmin
Grants and funding
P30 CA044579/CA/NCI NIH HHS/United States
K08 CA215317/CA/NCI NIH HHS/United States
P30 CA008748/CA/NCI NIH HHS/United States
R35 CA197594/CA/NCI NIH HHS/United States
R03 CA252825/CA/NCI NIH HHS/United States
F31 CA271809/CA/NCI NIH HHS/United States
T32 CA009109/CA/NCI NIH HHS/United States
F99 CA284252/CA/NCI NIH HHS/United States
P01 CA171983/CA/NCI NIH HHS/United States