Endometrial receptivity in women with endometriosis

Best Pract Res Clin Obstet Gynaecol. 2024 Feb:92:102438. doi: 10.1016/j.bpobgyn.2023.102438. Epub 2023 Nov 29.

Abstract

As endometriosis is recognized as a contributing factor to infertility, prompting couples to embark on Assisted Reproductive Technology (ART) treatments, it becomes crucial to comprehend the extent and way this condition can affect success rates. Natural conception data reveal lower success rates for women with endometriosis, yet the same cannot be extrapolated to the outcomes of in vitro fertilization (IVF). In recent years, advancements in the ART process, particularly the distinct stages of the IVF pathway and investigations into embryo quality have shown a comparable rate of embryonic quality and chromosomal normalcy (euploidy) between embryos obtained from individuals with or without endometriosis. Thus, the primary question that lingers relates to the functionality of the endometrium. This review addresses whether endometriosis can influence endometrial receptivity and implantation rates.

Keywords: Endometrial receptivity; Endometriosis; Endometrium; Implantation; Infertility; Live birth rate.

Publication types

  • Review

MeSH terms

  • Embryo Implantation
  • Endometriosis* / complications
  • Endometrium
  • Female
  • Fertilization in Vitro
  • Humans
  • Infertility, Female* / etiology
  • Infertility, Female* / therapy
  • Pregnancy
  • Pregnancy Rate