Dexamethasone for postoperative nausea and vomiting prophylaxis in cesarean delivery and a delayed diagnosis of neonatal congenital adrenal hyperplasia

A C Waselewski; T T Klumpner; J A Kountanis; E S Sandberg; D E Shumer

doi:10.1016/j.ijoa.2023.103969

Dexamethasone for postoperative nausea and vomiting prophylaxis in cesarean delivery and a delayed diagnosis of neonatal congenital adrenal hyperplasia

Int J Obstet Anesth. 2024 Feb:57:103969. doi: 10.1016/j.ijoa.2023.103969. Epub 2023 Dec 13.

Authors

A C Waselewski¹, T T Klumpner², J A Kountanis², E S Sandberg³, D E Shumer³

Affiliations

¹ University of Michigan, Department of Pediatric Endocrinology, Ann Arbor, Michigan, USA. Electronic address: [email protected].
² University of Michigan, Department of Anesthesiology, Ann Arbor, Michigan, USA.
³ University of Michigan, Department of Pediatric Endocrinology, Ann Arbor, Michigan, USA.

PMID: 38195332
DOI: 10.1016/j.ijoa.2023.103969

Abstract

The case of a false-negative newborn screen for congenital adrenal hyperplasia in a 37 weeks' gestation 46,XX neonate, thought to be due to maternal administration of dexamethasone intra-operatively prior to umbilical cord clamping, for postoperative nausea and vomiting prophylaxis after neuraxial anesthesia, is described.

Publication types

Case Reports

MeSH terms

Adrenal Hyperplasia, Congenital* / complications
Adrenal Hyperplasia, Congenital* / diagnosis
Adrenal Hyperplasia, Congenital* / drug therapy
Antiemetics* / therapeutic use
Cesarean Section
Delayed Diagnosis
Dexamethasone / therapeutic use
Female
Humans
Infant, Newborn
Postoperative Nausea and Vomiting / drug therapy
Postoperative Nausea and Vomiting / prevention & control
Pregnancy

Substances

Dexamethasone
Antiemetics