Follow the allosteric transitions to predict variant pathogenicity: a channel-specific approach
Brain
.
2024 May 3;147(5):e37-e40.
doi: 10.1093/brain/awae008.
Authors
Nathan L Absalom
1
2
,
Serene El-Kamand
1
,
Han Chow Chua
3
,
Philip K Ahring
2
Affiliations
1
School of Science, Western Sydney University, Penrith, NSW, 2751, Australia.
2
School of Medical Sciences, Faculty of Medicine and Health, Brain and Mind Centre, The University of Sydney, Camperdown, NSW, 2050, Australia.
3
Sydney Pharmacy School, Faculty of Medicine and Health and Charles Perkins Centre, The University of Sydney, Sydney, NSW, 2006, Australia.
PMID:
38198781
PMCID:
PMC11068099
DOI:
10.1093/brain/awae008
No abstract available
Publication types
Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural
Editorial
Comment
MeSH terms
Allosteric Regulation
Humans
Ion Channels / metabolism
Mutation*
Substances
Ion Channels
Grants and funding
APP1185122/Australian National Health & Medical Research Council
R383-2022-276/The Lundbeck Foundation