CSF3R P733T is a deleterious germline variant in acute leukaemia showing gain-of-function-like T618I mutation

Br J Haematol. 2024 Mar;204(3):e31-e33. doi: 10.1111/bjh.19315. Epub 2024 Jan 23.

Authors

Haimin Sun¹, Yongmei Zhu², Jianfeng Li², Lingling Zhao², Zeying Yan¹, Sujiang Zhang^{1

2}

Affiliations

¹ Department of Hematology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
² National Research Center for Translational Medicine at Shanghai, Department of Hematology, Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

PMID: 38262633
DOI: 10.1111/bjh.19315

No abstract available

Publication types

Letter

MeSH terms

Gain of Function Mutation
Germ Cells
Humans
Leukemia*
Leukemia, Neutrophilic, Chronic* / genetics
Mutation
Receptors, Colony-Stimulating Factor / genetics
Signal Transduction

Substances

Receptors, Colony-Stimulating Factor
CSF3R protein, human

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